SoluCel discovers and develops secondary metabolites from plants for pharmaceutical applications. Several proprietary and generic products are currently in research.
Based on its technology platform, SoluCel establishes partnerships with pharmaceutical, agrochemical, fine chemical, food, nutraceutical, personal care, cosmetic and flavor & fragrance companies.
Applications of SoluCel’s technology platform include:
• In vitro plant cell and tissue cultures
SoluCel has a long experience in developing cell and tissue (e.g. roots, shoots) cultures from various plant species, including a substantial number of medicinal plant species. Cryopreservation methods have been established for different types of cell cultures.
• Discovery of novel and improved secondary metabolites
Combined with specific partner activity and functionality screens, SoluCel’s technology platform can generate novel or improved lead compounds for further product development.
• Cost-effective production of secondary metabolites and their intermediates
SoluCel provides the tools to metabolically engineer plant cells to realize commercially viable production of desired metabolites or to accumulate intermediate products that can be used for chemical derivatization.
• Elimination of undesired secondary metabolites such as anti-nutritional or toxic compounds
SoluCel’s technologies allow the identification and down-regulation of the expression of genes involved in the synthesis of undesired metabolites, for example off-color or off-flavor compounds in food ingredients.
• Biotransformation using SoluCel’s unique set of biocatalysts
SoluCel’s gene collection currently consists of more than 6,000 sequenced gene tags from medicinal plants. These genes encode many unique enzymes that can be used in different forms for the conversion of substrates into desired and/or novel compounds.
• Identification of genetic or metabolite markers for quality and productivity
Genetic and metabolite markers, identified using SoluCel’s metabolomics and transcriptomics technologies, can be used to screen e.g. varieties, breeding populations, differently processed products for their capacity to produce a secondary metabolite at a high level and/or their capability to generate a desired quality.
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